Effect of different blood purification methods on serum cardiac troponin T/I,β2-microglobulin and interleukin-6 levels in patients with maintenance hemodialysis
- VernacularTitle:不同血液净化方式对维持性血透患者血清心肌肌钙蛋白T/I、β2微球蛋白及白介素-6水平的影响
- Author:
Weizhong JIANG
;
Lijing CHEN
;
Xiangdong SHI
- Publication Type:Journal Article
- Keywords:
blood purification;
hemodialysis;
cardiac troponin T/I;
β2-microglobulin;
interleukin-6
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;35(10):73-75
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyse the effect of different blood purification methods on serum cardiac troponinc T (cTnT), cardiac troponinⅠ(cTnI), β2-microglobulin (β2-MG) and interleukin-6 (IL-6) levels in patients with maintenance hemodialysis.Methods 60 uremic patients treated with maintenance hemodialysis were collected.All patients were randomly divided into conventional hemodialysis group (HD group) , hemodialysis and hemoperfusion group (HD+HP group) and hemodiafiltration group (HDF group) , 20 cases in each group.Corresponding dialysis treatment was given, then the serum levels of cTnT, cTnI,β2-MG and IL-6 were detected in all patients post-treatment.Results After treatment, the serum cTnT, cTnI,β2-MG and IL-6 levels in HD+HP group and HDF group were lower than those in HD group (P<0.05).Conclusions Different blood purification methods have different effects on serum cTnT, cTnI, β2-MG and IL-6 levels in patients with maintenance hemodialysis, HDF and HD +HP have better scavenging effect, which has the guiding significance to clinical application.
