Epithelial-myoepithelial carcinoma of salivary glands, report of 23 cases

VernacularTitle:头颈部上皮-肌上皮癌的诊治分析
Author: Song NI ; Yiming ZHU ; Jian WANG ; Shaoyan LIU
Publication Type:Journal Article
Keywords: Salivary Gland Neoplasms; Radiotherapy; Chemotherapy,Adjuvant; epithelial-myoepithelial carcinoma
From: Chinese Archives of Otolaryngology-Head and Neck Surgery 2015;(11):563-565
CountryChina
Language:Chinese
Abstract: OBJECTIVE Epithelial-myoepithelial carcinoma (EMC) is a rare malignant neoplasm of the salivary glands. The aim of the study was to investigate the diagnosis, treatment and prognosis of EMC of the parotid gland.METHODSThe clinical data of 23 cases of EMC of the parotid gland from 1999 to 2013 were analyzed retrospectively. Of all the patients, 13 cases received radical surgery only, 9 cases received postoperative radiotherapy, and one case received postoperative chemotherapy. Kaplan-Meier survival curve was used to analyze the clinical data. RESULTSThe overall survival rate at 5-year was 81.0% and the overall no recurrence survival rate at 5-year was 67.3%. The recurrence rate was 39.1% (9/23). The 5-year no recurrence survival rate of radical surgery group was 55.6%, compared with 80.0% in the combined modality therapy group, there was no significant deference (χ2=2.232, P=0.135).CONCLUSIONThe postoperative recurrence rate of EMC is high. Radical surgery could be the main treatment of EMC, when the surgical margin couldn't be achieved, adjuvant radiotherapy or chemotherapy might be helpful.