In vitro activity of antimicrobial agents against Enterococcus spp

VernacularTitle:抗菌药物对肠球菌属细菌体外抗菌活性
Author: Wei GE ; Xiaoxiao ZHANG ; Dingcheng WANG ; Hailian SHAO ; Ying LI ; Ming YANG ; Zhi CHENG ; Bo SU ; Mingle FAN ; Shanhong FAN
Publication Type:Journal Article
Keywords: Enterococcus spp .; daptomycin; antimicrobial agent; drug resistance,microbial; rational drug use
From: Chinese Journal of Infection Control 2015;(11):753-756
CountryChina
Language:Chinese
Abstract: Objective To investigate in vitro activity of antimicrobial agents against Enterococcus spp . isolated from clinic specimens in a hospital.Methods 188 Enterococcus spp . isolates from specimens sent by clinic depart-ments in June 2013-July 2014 were identified and performed antimicrobial susceptibility testing.Results Of 188 En-terococcus spp . isolates,119 were Enterococcus faecium (E.faecium),60 were E.faecalis ,and 9 were E.avium, these strains were mainly isolated from urine (34.57%)and blood specimens (19.15% ).No daptomycin and linezolid-resistant strain was detected;resistant rates of E.faecium to vancomycin was 1 .68%,to penicillin, ampicillin,high concentration gentamycin,erythromycin,and levofloxacin were all > 70%;except tetracycline, resistant rates of E.faecalis to the other antimicrobial agents were all lower than E.faecium,resistant rates of E. faecalis to penicillin and ampicillin were 16.67% and 13.33% respectively.Conclusion Daptomycin has high activity against Enterococcus spp . in this hospital.