Effect of Xiaoyao pill on SOD, MDA, interleukin family and clinical efficacy in patients with pelvic inflammation
- VernacularTitle:逍遥丸对盆腔炎患者血清SOD、MDA、白介素族指标及临床疗效的影响
- Author:
Jingzhi HE
;
Yanping WU
;
Chao LI
- Publication Type:Journal Article
- Keywords:
Xiaoyao pill;
pelvic inflammation;
superoxide dismutase;
malondialdehyde;
interleukin
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;35(10):22-24
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate effect of Xiaoyao pill on superoxide dismutase (SOD), malondialdehyde (MDA), interleukin family and clinical efficacy in patients with pelvic inflammation.Methods 75 cases with pelvic inflammation were selected and divided into experimental group and control group randomly according to random number table method.37 cases in control group were treated with conventional anti-inflammatory and Qianjin pill, 38 cases in experimental group were treated with conventional anti-inflammatory and Xiaoyao pill, 14 days for a course.SOD, MDA and interleukin family were compared and the effective rate and adverse reaction rate were compared.Results Compared with control group post-treatment, SOD in serum in experimental group was higher(P<0.05),MDA in serum was lower(P<0.05);IL-1 and IL-8 were lower(P<0.05);IL-4 and IL-10 were higher(P<0.05).The total efficiency of experimental group was significantly higher than that of control group, the adverse reactions were lower (P<0.05).Conclusion Xiaoyao pill has good curative effect on the patients with pelvic inflammatory disease,the mechanism may be related to the elevation of serum SOD,IL-4, IL-10 levels and reduce the levels of MDA,IL-1,IL-8.
