Advances in Study on Wnt Signaling Transduction Pathway and Colorectal Cancer
10.3969/j.issn.1008-7125.2015.10.015
- VernacularTitle:Wnt 信号转导通路与结直肠癌的研究进展
- Author:
Lingli LI
;
Xiaoyan CHEN
;
Rong ZHU
;
Kui ZHAO
- Publication Type:Journal Article
- Keywords:
Colorectal Neoplasms;
Wnt Signaling Pathway;
beta Catenin;
Stem Cells
- From:
Chinese Journal of Gastroenterology
2015;(10):635-637
- CountryChina
- Language:Chinese
-
Abstract:
Colorectal cancer is one of the most commonly seen gastrointestinal carcinomas and its pathogenesis has not yet been fully clarified. It is considered as a multi-step and multi-stage disease. Wnt signaling transduction pathway regulates cell growth,motility and differentiation,and plays a crucial role in the regulation of embryonic development and tumor genesis. This article reviewed the advances in study on Wnt signaling transduction pathway and colorectal cancer.
