Study on Early Predictive Value of Clinical Indicators for Acute Kidney Injury in Patients with Acute Pancreatitis
10.3969/j.issn.1008-7125.2015.10.004
- VernacularTitle:急性胰腺炎相关指标对急性肾损伤早期预测价值的研究
- Author:
Mengjuan LIN
;
Zhenpeng HUANG
;
Baoping YU
- Publication Type:Journal Article
- Keywords:
Acute Pancreatitis;
Acute Kidney Injury;
D-Dimer;
Procalcitonin;
Calcium
- From:
Chinese Journal of Gastroenterology
2015;(10):592-596
- CountryChina
- Language:Chinese
-
Abstract:
Background:Acute kidney injury(AKI)is one of the early serious complications of acute pancreatitis(AP). Early identification and intervention have important clinical significance. Aims:To investigate the early predictive value of clinical indicators found within 48 hours after admission for AKI in patients with AP. Methods:A retrospective analysis of 205 AP patients from January 2014 to December 2014 at Renmin Hospital of Wuhan University was performed. AP patients were divided into AKI group and non-AKI group according to the KDIGO standard,the demographic characteristics,history of chronic diseases and indicators defined within 48 hours after admission such as Ranson score,BISAP score and biochemical indices were compared. The early predictive value of clinical indicators for AKI was evaluted,and strength of association between clinical indicators and AKI was assessed. Results:Compared with non-AKI group,Ranson score, BISAP score,D-dimer,PCT,blood glucose,triacylglycerol were significantly increased in AKI group(P < 0. 05),and calcium was significantly decreased(P < 0. 05). The accuracies of D-dimer,PCT,calcium were high for early prediction of AKI,and the AUC were 0. 881,0. 803 and 0. 782,respectively. Logistic regression analysis showed that D-dimer, PCT,calcium had marked correlation with AKI(OR all > 7)(P < 0. 05). Conclusions:D-dimer,PCT and calcium are effective and economical clinical indicators for the early prediction of AKI in patients with AP.
