Risk factors and prognosis of patients with bloodstream infection due to carbapenem-resistant Acinetobacter baumannii
10.3969/j.issn.1671-9638.2015.10.005
- VernacularTitle:耐碳青霉烯类鲍曼不动杆菌血流感染患者危险因素及预后
- Author:
Wenzhi HUANG
;
Fu QIAO
;
Yantong WANG
;
Weijia YIN
;
Zhiyong ZONG
- Publication Type:Journal Article
- Keywords:
Acinetobacter baumannii;
bloodstream infection;
carbapenems;
carbapenem-resistant Acinetobacter baumannii;
risk factor;
prognosis
- From:
Chinese Journal of Infection Control
2015;(10):668-671
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the risk factors and prognosis of hospitalized patients with bloodstream infection due to carbapenem-resistant Acinetobacter baumannii (CRAB).Methods 163 patients with CRAB bloodstream in-fection from 2010 to 2013 were conducted retrospective case-control study,68 patients with bloodstream infection due to carbapenem-susceptible Acinetobacter baumannii (CSAB)during the same period were as control group. Results The independent risk factors for CRAB bloodstream infection were stay in intensive care unit(ICU)(OR, 1 .27[95%CI ,5.55-22.89])and emergency department(OR,3.57 [95%CI ,1 .67 -7.62])before infection.Pa-tients with CRAB bloodstream infection had lower 28-day survival rate than those with CSAB bloodstream infection (66.17% vs 96.95%,χ2 =15.71 ,P <0.001 ).The independent risk factors for influencing prognosis of Acineto-bacter baumannii bloodstream infection were infection of CRAB (HR 95% CI ,3.01 -67.28),blood disease(HR 95%CI ,3.77-25.97),cardiac insufficiency(HR 95%CI ,2.10-20.41),stay in ICU(HR 95%CI ,1 .01 -5.28), and age(HR 95%CI ,1 .01 -1 .04).Conclusion The independent risk factors for CRAB bloodstream infection are stay in ICU and emergency department before infection,CRAB bloodstream infection is risk factor for influencing prognosis of patients.
