Clinical study on Honggui capsule combined with chemotherapy for lung cancer
10.3760/cma.j.issn.1673-4246.2015.11.008
- VernacularTitle:红归胶囊配合化疗治疗肺癌临床研究
- Author:
Bin WANG
;
Xiaoyuan LI
;
Yang LIU
;
Fengyun ZHANG
;
Jing WANG
- Publication Type:Journal Article
- Keywords:
Lung neoplasms;
Honggui capsule;
Antineoplastic combined chemotherapy protocols;
Quality of life;
Comparative effectiveness research
- From:
International Journal of Traditional Chinese Medicine
2015;(11):991-993
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical efficacy of Honggui capsule combined with chemotherapy in the treatment of lung cancer. Methods 61 cases of lung cancer patients were randomly divided into group A of 30 cases, treated with Honggui Capsule and chemotherapy, and group B of 31 cases treated with chemotherapy only by the envelope method. After both groups were treated for 21 days, the clinical effect, life quality improvement, improvement of TCM symptoms and the incidence of toxic and side effects in 2 groups were compared. Results After treatment, there was significant difference between group A and B in the tumor response rate (26.7% vs. 3.2%; χ2=4.927, P=0.026), Karnofsky (23.3% vs. 3.3%; χ2=5.410, P=0.020), and improvement of TCM symptoms (13.3% vs. 0.0%; χ2=4.423, P=0.035). During treatment, there was significant difference between group A and B in bone marrow suppression (33.3% vs. 58.1%; χ2=4.778, P=0.029), and gastrointestinal disturbance (16.7% vs. 58.1%; χ2=11.124, P=0.001). Conclusion Honggui capsule combined with chemotherapy has an enhanced efficacy and a detoxicating effect, besides it improves clinical symptoms and reduces the side effects of chemotherapy.
