The quality standard study of Huangqi-Changyu'an capsule Yutian Hospital of TCM of Hebei Province, Tangshan 064100, China
10.3760/cma.j.issn.1673-4246.2015.11.014
- VernacularTitle:黄芪肠愈安胶囊质量标准研究
- Author:
Jinfeng ZHANG
;
Zhiyong SONG
- Publication Type:Journal Article
- Keywords:
HPLC;
Huangqi-Changyu'an capsule;
Psoralens;
Angelicin
- From:
International Journal of Traditional Chinese Medicine
2015;(11):1015-1018
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish the quality standard of Huangqi-Changyu'an capsule. Method Thin layer chromatography was used to identify psoralen, evodia mtaecarpa, and nutmeg in Huangqi-changyu'an capsule. HPLC was used to determine the content of psoralen. A Hypeisil BDS C18 column(200 mm×4.6 mm,5 μm) was used with mobile phase consisted of acetonitrile-water (30:70) at the rate of 1 ml/min. The detection wavelength was set at 245nm with the column at room temperature. Results The liner range of psoralen was 3.572~53.58 μg/ml (r=0.999 9) with average recoveries of 99.04%, and the RSD was 0.8%. The liner range of isopsoralen was 3.796~56.94 μg/ml (r=0.999 9) with average recoveries of 99.20%, and the RSD was 0.6%. Conclusion This method is sentivive, accurate and rapid for the quality control of Huangqi-Changyu'an capsule.
