Distribution and antimicrobial resistance of 965 pathogenic strains from wound infection
10.3969/j.issn.1671-9638.2015.10.013
- VernacularTitle:965株创面感染病原菌分布及耐药性
- Author:
Zhaoyun XIE
;
Fei YAN
;
Yongfa XIONG
;
Yun XIONG
;
Jing SUN
;
Zhongling YANG
- Publication Type:Journal Article
- Keywords:
wound infection;
drug resistance,microbial;
pathogen;
drug resistance;
healthcare-associated infection
- From:
Chinese Journal of Infection Control
2015;(10):697-700
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the distribution and antimicrobial resistance of pathogenic strains in wound infec-tion,and provide scientific evidence for rational use of antimicrobial agents in treatment of wound infection as well as reducing the emergence of drug-resistant organisms.Methods Data about pathogenic strains isolated from wound specimens of patients with wound infection in a hospital between June 2011 and April 2014 were analyzed retrospectively.Results A total of 965 pathogenic strains were isolated from wound specimens,the main infection sites were limbs(50.47%);infected patients mainly distributed in department of orthopaedic surgery(44.97%);trauma and incisional wound infection were the major infection types(47.98%,36.48%,respectively).Among iso-lated pathogens,gram-positive bacteria,gram-negative bacteria,and fungi accounted for 37.20%,59.59%,and 3.21 % respectively.The main gram-positive bacteria were highly susceptible to vancomycin,teicoplanin,and linezolid,the main gram-negative bacteria were highly resistant to most commonly used antimicrobial agents except cefoperazone/sulbactam,piperacillin/ tazobactam,imipenem,and meropenem.Conclusion Patients with wound infection are mainly distributed in department of orthopedics,the main infection types are trauma and surgical site infection,antimicrobial resistant rates of the major gram-positive and gram-negative bacteria are both high.Sur-geons,especially orthopedics surgeons,should pay attention to the culture of pathogens and monitoring of antimi-crobial susceptibility,use antimicrobial agents rationally,and strengthen the prevention and control of surgical site infection,so as to reduce the infection incidence and occurrence of drug-resistant organisms.
