Retrospective analysis on healthcare-associated infection in a cancer hospi-tal between 2006 and 2012
10.3969/j.issn.1671-9638.2015.10.015
- VernacularTitle:2006-2012年某肿瘤医院医院感染回顾性分析
- Author:
Xuesong FU
;
Huimin ZENG
;
Ji ZHANG
;
Yunfeng YAO
;
Li ZHANG
;
Fengxin YANG
;
Yunxia DU
- Publication Type:Journal Article
- Keywords:
cancer;
patient;
healthcare-associated infection;
pathogen;
drug resistance,microbial;
antimicrobial agent
- From:
Chinese Journal of Infection Control
2015;(10):704-707
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate healthcare-associated infection(HAI)in patients in a cancer hospital,provide reference for controlling HAI in cancer patients,and guide rational use of antimicrobial agents.Methods Clinical data of patients in a cancer hospital between August 2006 and July 2012 were analyzed retrospectively.Results The incidence of HAI case was 1 .53% (2 060/134 389),and annual incidence showed a downward trend.The main in-fection site was lower respiratory tract (46.46%,n=957),followed by bloodstream (15.63%,n=322),abdominal and pelvic (14.03%,n=289).The main pathogens were Pseudomonas aeruginosa (16.16%,n=350),Staphylo-coccus aureus (9.97%,n=216),Klebsiella pneumoniae (9.79%,n=212),Escherichia coli (9.65%,n=209), and Candida albicans (6.51 %,n=141 ).Gram-negative bacilli,including Klebsiella pneumoniae and Escherichia coli ,were sensitive to carbapenems and β-lactamase inhibitors.Conclusion Lower respiratory tract is the major HAI site in patients with cancer,and gram-negative bacteria are the main pathogens.Carbapenems andβ-lactamase inhibitors are recommended for the empirical treatment of HAI in cancer patients.
