Carbon nanoparticles in central lymph node dissection in treatment of papillary thyroid carcinoma
10.3760/cma.j.issn.1674-6090.2015.05.012
- VernacularTitle:纳米碳混悬液在甲状腺乳头状癌中央区淋巴结清扫中疗效评价
- Author:
Hongqiang LI
;
Detao YIN
;
Yongfei WANG
;
Wenming GE
;
Hao ZHU
;
Jianhui XU
;
Xianghua LI
;
Kun YU
- Publication Type:Journal Article
- Keywords:
Carbon nanoparticles;
Papillary thyroid carcinoma;
Lymph node metastasis;
Parathy-roid gland preservation
- From:
Chinese Journal of Endocrine Surgery
2015;(5):398-400
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the curative effects of carbon nanoparticles on central lymphnode dis -section in papillary thyroid carcinoma ( PTC) .Methods 72 PTC patients were randomly divided into two groups:carbon nanoparticle group(n=32)and the control group(n=32).Patients in the carbon nanoparticle group were injected with carbon nanoparticles during surgery .Patients in the control group had conventional surgery .The number of lymph nodes being dissected ,lymph node metastasis , and the rate of hypoparathyroidism were compared between the two groups .Results The number of lymph nodes dissected in nanoparticle group ( n =312 ) was much bigger than that in the control group (n=189)(P<0.01;t=8.476).The incidence of hypoparathyroidism in nanoparticle group(n=1)was much lower than that in the control group (n=8)(P<0.05;χ2 =4.571).The metastasis of lymph nodes has no significant difference between the two groups (P>0.01;χ2 =1.048).Conclu-sions The lymphatic tracer technique may improve the number of lymph nodes dissected in central region of PTC and reduce parathyroid gland damage .
