Clinical and pathological analysis on diagnosis and treatment of 58 breast cancer patients over 80 years old
10.3760/cma.j.issn.1674-6090.2015.05.009
- VernacularTitle:58例年龄大于80岁乳腺癌的临床病理分析及诊治体会
- Author:
Qing LYU
;
Linfang JIN
;
Dong MENG
- Publication Type:Journal Article
- Keywords:
Elderly breast cancer;
Clinicopathological characteristics
- From:
Chinese Journal of Endocrine Surgery
2015;(5):385-389
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical and pathological features of breast cancer in patients over 80 years old, to discuss the individualized treatment plan and further to provide foundation for clinical treatment . Methods Data of 58 breast cancer patients over 80 years old were retrospectively analyzed .They were treated from Jun.2008 to May.2014 and the diagnosis was confirmed by pathology after surgery .They were followed up by telephone.Results Among the 58 cases, invasive cancer accounted for 94.8%(55/58), in which triple-negative breast cancer accounted for 29.1%(16/55), and human epidermal growth factor receptor 2(HER2)pos-itive breast cancer accounted for 7.2%( 4/55 ) .Stage III breast cancer accounted for 24%( 14/58 ) .67.2%(39/58)patients underwent breast resection , 55.2%(32/58)patients underwent axillary treatment , 17.2%(10/58)patients received chemotherapy , and 51.7%(30/58) patients received endocrine therapy .Seven cases had recurrence and 3 cases died of the disease .Conclusions Breast cancer in elderly patients has its special clinical and pathological features .It has longer course , relatively late stage , and more complications .It has higher pro-portion of triple-negative breast cancer and lower proportion of positive HER 2.Elderly breast cancer patients are less tolerant to chemotherapy , thus surgery and endocrine therapy are the main treatment .
