Correlation between oxygen reduction index with blood lipid and renal function in OSAHS patients
10.3969/j.issn.1671-8348.2015.28.014
- VernacularTitle:OSA HS 患者不同程度氧减指数与血脂、肾功能相关性研究
- Author:
Yuanyuan YE
;
Xiaojiang JIANG
;
Dong GAO
;
Xunjun LI
;
Yazhen LIU
;
Ying LANG
;
Ling LIN
;
Xinju YANG
- Publication Type:Journal Article
- Keywords:
obstructive sleep apnea hypopnea syndrome;
oxygen reduction index;
nocturnal intermittent hypoxia
- From:
Chongqing Medicine
2015;(28):3938-3940
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the correlation between oxygen reduction index(ODI) with blood lipid and renal function in patients with obstructive sleep apnea hypopnea syndrome(OSAHS) .Methods Selected 208 patients by polysomnography (PSG) and diagnosed as OSAHS ,divided into four groups according to ODI(ODI ≤ 7 ,7 < ODI ≤ 18 ,18 < ODI ≤ 38 and ODI > 38) .Four groups were compared in total cholesterol (TC) ,triglyceride (TG) ,high‐density lipoprotein cholesterol (HDL‐C) ,low density lipo‐protein cholesterol (LDL‐C) ,apolipoprotein A1 (ApoA1) ,apolipoprotein B (ApoB) ,urea ,creatinine ,uric acid and other differ‐ences ,analysis the correlation between ODI with blood lipid and renal function .Results There were significant different in TC ,TG , HDL‐C ,LDL‐C ,ApoB ,urea ,creatinine ,uric acid in four groups with different degree of ODI (P< 0 .05) ;ODI were positively relat‐ed to TC ,TG ,LDL‐C ,ApoB ,urea ,creatinine ,uric acid levels ,and negatively related to the level of HDL‐C .Conclusion Abnormity of blood lipid metabolic and changes in renal function are associated with the increase of ODI in patients with OSAHS .
