Meta analysis of clinical and pathological features of breast cancer in young women in China
10.3969/j.issn.1671-8348.2015.28.021
- VernacularTitle:中国年轻女性乳腺癌临床及病理特征的 Meta 分析
- Author:
Ting WANG
;
Denghui LIAO
;
Yadong WANG
;
Lin GAN
;
Jie MIN
;
Zhen ZENG
;
Gang LV
- Publication Type:Journal Article
- Keywords:
breast neoplasms;
young women;
clinical and pathological features;
Meta analysis
- From:
Chongqing Medicine
2015;(28):3959-3961
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the clinical and pathological features of Chinese young breast cancer(age ≤ 35)with elder patients(> 35)using Meta analysis .Methods Published studies concerning clinical and pathological features of young breast cancer in China were searched systemically and assessed .Stata12 .0 software was used for data analyzing and calculating OR and its 95%CI .Results Totally 31 studies were selected for Meta analysis ,and most of them were classified as 6 - 7 scores ,which showed the quality of articles was high .The risk factors of breast cancer and its pooled odds ratio values with statistical significance were as fol‐lows 6 .42(95% CI :4 .22 - 9 .79) ,0 .61(95% CI :0 .50 - 0 .74)when clinical staging of 0 - Ⅱ phase or Ⅰ - Ⅱ phase ,2 .25(95% CI :1 .69 - 2 .99)when histological type of Invasive carcinoma ,1 .73(95% CI :1 .23 - 2 .43)when histological grade of III grade ,1 .80 (95% CI :1 .23 - 2 .43)when positive of lymph node metastasis .Conclusion Compared with elder breast cancer ,the clinical and pathological characteristics of young breast cancer were mainly for the high misdiagnosis rate ,the late clinical stage ,the high pro‐portion invasive carcinoma ,the poor histological differentiation and the lymph node metastasising easily ,the hint of young breast cancer screening and treatment may be different principles and measures should be adopted .
