The relationship between red cell distribution and serum inflammatory factors in dilated cardiomyopathy patients
10.3969/j.issn.1673-4130.2015.20.003
- VernacularTitle:扩张性心肌病患者血液红细胞分布宽度改变与血清炎性因子之间的关系
- Author:
Hualing GUAN
;
Shengyang JIANG
- Publication Type:Journal Article
- Keywords:
dilated cardiomyopathy;
red cell distribution width;
inflammatory factor
- From:
International Journal of Laboratory Medicine
2015;(20):2926-2928
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between red cell distribution (RDW) and serum inflammatory factor in di‐lated cardiomyopathy (DCM ) patients .Methods 47 dilated cardiomyopathy patients and 40 healthy volunteers were chosen .Ac‐cording to NYHA classification ,12 patients in NYHA class Ⅱ ,15 patients in NYHA class Ⅲ and 20 patients in NYHA class Ⅳ . RDW ,High sensitivity C‐reaction protein (hs‐CPR) ,tumor necrosis factor‐α (TNF‐α) and interleukin‐1β (IL‐1β) were detected in all the DCM patients and healthy volunteers .The correlation between RDW and serum inflammatory factors were analyzed . Results Compared to healthy volunteers ,RDW ,hs‐CRP ,TNF‐α and IL‐1β were elevated significantly in DCM patients (all P<0 .05) .Comparisons among the DCM patients groups ,RDW ,hs‐CRP ,TNF‐α,IL‐1β in NYHA class Ⅲ and NYHA class Ⅳ were higher than those in NYHA class Ⅱ(all P<0 .05) .There were positive correlation between RDW and hs‐CRP ,RDW and TNF‐α, RDW and IL‐1β(r=0 .422 ,0 .390 ,0 .325 ,P<0 .05) .Conclusion RDW is one of the indicators evaluating cardiac functions ,and there is a significant correlation between RDW and serum inflammatory factors in DCM patients .
