Clinical observations of spraying Zhikang Capsules guided by gastroscopy in treatment elderly upper gastrointestinal bleeding
10.3760/cma.j.issn.1008-6315.2015.05.011
- VernacularTitle:胃镜下喷洒致康胶囊混悬液治疗老年人上消化道出血的效果观察
- Author:
Hongli CHEN
;
Jianguang TANG
;
Yangli DUAN
- Publication Type:Journal Article
- Keywords:
Upper gastrointestinal bleeding;
Spray with gastroscopy;
Zhikang Capsules;
Elderly
- From:
Clinical Medicine of China
2015;31(5):417-419
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical effect and security of spraying Zhikang Capsules guided by gastroscopy in treatment elderly upper gastrointestinal bleeding.Methods Eighty-four elderly gastric duodenal ulcer bleeding patients were randomly assigned to group A,B and C (n =28 for each group).Patients in group A were used noradrenalin to spray with gastroscopy,in group B were used thrombin and in group C were used Zhikang Capsules.The total effective,the immediate homeostasis rate,the incidence of rebleeding,the emergency operation rate and the incidence of adverse reaction were recorded and analyzed.Results Total effective rate of group C was 96.4％ (27/28),significantly higher than that in group A (71.4％,20/28),B (75.0％,21/28) and the difference was significant(P＜0.05).The incidence of rebleeding in group A,B,C were 28.6％ (8/28),17.9％ (6/28),3.6％ (1/28) respectively,and the difference was significant (P ＜0.05).The same trend was seen regarding of the incidence of adverse reaction among three groups (25.0％,7/28;10.7％,3/28;0,0/28;P＜0.05).Conclusion Spraying Zhikang Capsules guided by gastroscopy is showed with good therapeutic effect in treating elderly upper gastrointestinal bleeding and high safety,and with less adverse reaction.
