The expression and role of CMTM family in tumor
10.3760/cma.j.issn.1673-422X.2015.09.010
- VernacularTitle:CMTM家族在肿瘤中的表达及作用
- Author:
Yabo ZHOU
;
Ye JIANG
;
Bingxin PANG
;
Qianqian WU
;
Jia LU
;
Jie HU
;
Wei LIU
- Publication Type:Journal Article
- Keywords:
Genes;
Neoplasms;
CMTM family
- From:
Journal of International Oncology
2015;42(9):679-681
- CountryChina
- Language:Chinese
-
Abstract:
CMTM family is silenced and down-regulated in several kinds of tumors.Its aberrant expression has a strong association with the development,progression and metastasis of tumors.Thus,CMTM family is potential tumor suppressor genes.Epigenetics mechanism is the essential mechanism of the aberrant expression in this gene family.The discovery of this research gives a new direction to the clinical treatment of tumor.