Therapeutic strategies and relevant clinical problems in non-small cell lung cancer with brain metastases
10.3969/j.issn.1000-8179.2015.19.743
- VernacularTitle:非小细胞肺癌脑转移的治疗策略与相关问题
- Author:
Fei TANG
;
Lin ZHOU
;
You LU
- Publication Type:Journal Article
- Keywords:
non-small cell lung cancer;
brain metastases;
radiotherapy;
targeted therapy;
molecular mechanism;
brain injury;
brain necrosis
- From:
Chinese Journal of Clinical Oncology
2015;42(19):947-952
- CountryChina
- Language:Chinese
-
Abstract:
Brain metastasis is among the most common complications of non-small celllung cancer (NSCLC) and may obviously influence the survival and quality of life in the NSCLC patients. Recently, the development in traditional treatments, the widely-used micro-molecular targeted drugs, and the combined treatment have improved the overall survival and the quality of life of these patients. In addition, the exploration of new therapeutic targets and cognitive function protective methods for current treatments also deserves at-tention. This review emphasizes the relevant clinical and basic problems and the therapeutic strategies in NSCLC with brain metastases.