Effects of lactobacillus complex capsules in patients with acute exacerbation of chronic obstructive pulmonary disease
10.3969/j.issn.1006-5725.2015.17.039
- VernacularTitle:复合乳酸菌治疗慢性阻塞性肺疾病急性加重的价值
- Author:
Jian LI
;
Jinping CHEN
;
Ling PENG
;
Daying LIU
- Publication Type:Journal Article
- Keywords:
Pulmonary disease,chronic obstructive;
Therapy;
Probiotics;
Lactobacillus
- From:
The Journal of Practical Medicine
2015;(17):2886-2889
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effects of lactobacillus complex capsules in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Methods A hundred AECOPD patients were divided into 2 groups: the therapy group(n = 50) with conventional and lactobacillus complex capsules therapy, and the control group with conventional therapy only. Parameters before and after therapy were compared, which included length of hospital stay, arterial blood gases, dyspnea grade, respiratory function test, markers of inflammation, anorexia score, diarrhea, fungi infection, breathing rate, death rate and side-effects of lactobacillus complex capsules. Results After 7 days of treatment, the blood leukocyte count and neutrophil ratio in the therapy group were lower than that of the control group (P < 0.05). The rate of anorexia score ≤ 2 in the therapy group was higher than that of the control group (P < 0.05). There were no differences in the rest parameters among the two groups(P > 0.05). There were no side-effects, such as skin rash and diarrhea, to be observed in the therapy group. Conclusion Oral lactobacillus complex capsule can be safe, anti-infective and improve appetite in patients with AECOPD.