Diagnostic value of biomarkers in children with fulminant myocarditis
10.3760/cma.j.issn.1673-4912.2015.08.002
- VernacularTitle:心肌损伤标志物在暴发性心肌炎中的诊断价值
- Author:
Yun CUI
;
Yucai ZHANG
- Publication Type:Journal Article
- Keywords:
Fulminant myocarditis;
Biomarkers;
Diagnosis;
Children
- From:
Chinese Pediatric Emergency Medicine
2015;22(8):527-530
- CountryChina
- Language:Chinese
-
Abstract:
Biomarkers are objective tools with an important role for diagnosis in patients with acute myocarditis.Traditional biomarkers,such as aspartate aminotransferase,creatine kinase and myoglobin seem to have low sensitivity.Creatine kinase-MB′s major limitation is short in half-life,which makes monitoring more difficult.To date,cardiac troponins are closest to optimal biomarker with high sensitivity and specificity in the early diagnosis of acute myocarditis.Novel biomarkers,including stromal cell-derived factor 1 ,heart-type fatty acid binding protein and MicroRNA have the potential to be valuable biomarkers for early diagno-sis.Combining biomarkers and clinical features have appeared to improve diagnostic accuracy than either one alone.
