The protein CagA enters the AGS cells via the interaction of the vesicles of Helicobacter pylori
- Author:
Juatina. L.M -- --
- Publication Type:Journal Article
- Keywords:
Helicobacter pylori, CagA
- MeSH:
Helicobacter pylori;
Cells;
Antigens, Bacterial;
Bacterial Proteins
- From:Journal of Medical Research
2003;23(3):50-54
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
The entry of gastric carcinoma cells ASG via the interaction of the vesicles of Helicobacter pylori VNH-85 strain was studied. The results showed that: The vesicles of Helicobacter pylori contained many protein toxins such formed from the outer membrane of bacterium H. pylori. The entry of them into gastric carcinoma cells ASG C120 led to increased synthesis of interleukin IL-8. So that, protein CagA could enter into gastric epithelium cells via interaction of bacteria, into gastric epithelium cells, protein CagA increased synthesis of interleukin IL-8 over 8 times.
