Hydrophilic acrylic intraocular lens:biocompatibility and complications following implantation
10.3969/j.issn.2095-4344.2015.34.026
- VernacularTitle:亲水性丙烯酸酯人工晶状体植入后的生物相容性和并发症
- Author:
Fen WEI
;
Ming AI
- Publication Type:Journal Article
- Keywords:
Phakic Intraocular Lenses;
Methylmethacrylates;
Histocompatibility;
Biocompatible Materials
- From:
Chinese Journal of Tissue Engineering Research
2015;(34):5547-5551
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND:Hydrophilic acrylic materials with good biocompatibility have been widely used in clinic. However, there are some problems about the biocompatibility and safety of hydrophilic acrylic intraocular lens after long-term clinical application. OBJECTIVE:To discuss the biocompatibility and stability issues and corresponding processing methods after hydrophilic acrylic intraocular lens implantation. METHODS:A computer-based search of Wanfang and PubMed database was performed for articles related to clinical application of hydrophilic acrylic intraocular lens published from 2005 to 2014. The keywords were “hydrophilic acrylic,intraocular lens” in Chinese and English, respectively. A total of 618 articles were initialy retrieved, and finaly 35 articles were included in result analysis. RESULTS AND CONCLUSION:As the hydrophilic acrylic intraocular lens is foldable, a smal incision is required for implantation and the operation is simple that cause less damage to the patients. In addition, the hydrophilic acrylic intraocular lens has poor bacterial and inflammatory cel adhesion, which leads to a low probability of infective endophthalmitis after implantation. But there is a high incidence of posterior capsule opacification as wel as some refractive errors and visual quality problems after implantation. Taken together, to solve these problems depends on the continuous improvements and updates of intraocular lens materials and designs.