Comparative study of two kinds of D2 lymphadenectomy in the treatment of patients with advanced gastric cancer
10.3760/cma.j.issn.1008-6706.2015.17.004
- VernacularTitle:两种D2淋巴结清扫术式用于进展期胃癌患者临床对比研究
- Author:
Wenxiong XU
;
Lin YANG
;
Baofeng GUO
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
Laparoscopy;
Laparotomy;
Lymph node excision
- From:
Chinese Journal of Primary Medicine and Pharmacy
2015;(17):2571-2573
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical effects differences of two kinds of D2 lymphadenectomy in the treatment of patients with advanced gastric cancer including open operation and laparoscopy operation.Methods 90 patients with advanced gastric cancer were chosen in recent years in our hospital and were randomly divided into both group including group A (45 patients)with D2 lymphadenectomy by open operation and group B (45 patients) with D2 lymphadenectomy by laparoscopy operation;and the clinical indicators in peri-operation period,the dissec-tion number of lymph node,survival rate in 1 year with follow-up and postoperative complication incidence of both groups were compared.Results The clinical indicators in peri-operation period of group B was significantly better than that of group A (t=2.13,2.56,1.98,1.96,1.94,2.05,2.10,all P<0.05).The N2 dissection number of lymph node of group B was significantly fewer than that of group A (t=2.15,P<0.05).The survival rate in 1 year with follow-up of group A and group B were separately 88.89%and 91.11%,there was no significant difference in survival rate in 1 year with follow-up between the two groups(χ2 =1.67,P>0.05).The postoperative complication incidence of group A and group B were separately 20.00% and 8.89%,the postoperative complication incidence of group B was significantly lower than that of group A (χ2 =9.44,P<0.05).Conclusion Compared with D2 lymph-adenectomy by open operation,D2 lymphadenectomy by laparoscopy operation in treatment of patients with advanced gastric cancer can efficiently decrease the degree of surgical trauma,accelerate the process of recovering after opera-tion,and be helpful to reduce the risk of postoperative complications.