The impact of different surgical method and different doses of euthyrox on bone mineral density

VernacularTitle:左甲状腺素对甲状腺癌术后患者骨密度的影响
Author: Dong LIU
Publication Type:Journal Article
Keywords: Thyroid surgical method; Euthyrox; Bone mineral density
From: Chinese Journal of Primary Medicine and Pharmacy 2015;(17):2577-2579
CountryChina
Language:Chinese
Abstract: Objective To investigate the impact of different surgical methods and different doses of euthyrox on bone mineral density.Methods A sample of 40 patients received thyroid cancer operation (excised affected side leaf,aisthmus,most of offside and neck VI lymph node dissection)and 40 patients received nodular goiter operation (excised affected side leaf)were collected,the dose of euthyrox taken in was 85 .2μg in thyroid cancer patients and 36.2μg in nodular goiter patients daily,the bone mineral density 6 month and 1 year after operation was detected. Results There was no difference of BMD between the two group 6 month after operation (P>0.05),but BMD of the observation group was (0.64 ±0.28)g/m2,which was lower than that of control group (t=2.235,P=0.03).Com-pared with pre-operation,BMD of control group had no change and the observation group appeared drop 1 year after operation.Conclusion Patients received thyroid cancer taking in euthyrox may show BMD reduced,especial 1 year after operation,doctors should be on the alert and supplement calcium appropriately.