DVH Obejective informed Planning in volume modulated arc therapy
10.3760/cma.j.issn.1004-4221.2015.06.022
- VernacularTitle:基于DVH目标函数的VMAT计划设计研究
- Author:
Jianhua JIN
;
Kaijue CHU
;
Haijiao SHAN
;
Haitao LIU
;
Jianting WU
;
Yongliang ZHAO
;
Gufei CAO
- Publication Type:Journal Article
- Keywords:
Volume modulated arc therapy;
Multi criteria optimization;
Overlapping dose volume histogram
- From:
Chinese Journal of Radiation Oncology
2015;(6):695-698
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the novel methods of VMAT planning based dose volume histogram ( DVH) optimization, evaluated the dosimetry and planning efficiency in VMAT planning for Esophageal Carcinoma. Methods Twelve Esophageal carcinoma patients were enrolled in this study. The conventional VMAT planning as the reference, using multi?criterion optimization DVH ( MCO?DVH ) and overlapping volume histogram prediction DVH ( OVH?DVH ) two different methods to get ideal objectives function for informing VMAT plans, Then evaluate the dosimetric, planning efficiency for all new VMAT plans. The difference between the paired t?test groups. Results The two VMAT plans based DVH objective function can meet the clinical needs. Compared with the conventional VMAT plan, Conformity index ( CI ) and Homogeneity index ( 0. 77 vs. 0. 72, P=0. 017 and 0. 10 vs. 0. 12, P=0. 047 ) is better in DVH informed plans;lung V5 and spinal cord V50 are better in MCO?DVH informed plan (54. 66 vs.60. 23,P=0. 013 and 0. 98 vs.0. 49,P=0. 037).Furthermore,the DVH informed plans had higher planning efficiency (8. 2 vs. 19. 5,P=0. 023) . Conclusions DVH Objective informed VMAT Planning can achieve clinical needs with much uniform dose to target,lower OAR dose and higher planning efficiency.
