Progress of diagnosis and treatment for maturity-onset diabetes of the young
10.3760/cma.j.issn.2095-428X.2015.20.003
- VernacularTitle:青少年发病的成人型糖尿病诊治进展
- Author:
Li LIANG
;
Chunlin WANG
- Publication Type:Journal Article
- Keywords:
Maturity - onset diabetes of the young;
Adolescence;
Gene;
Pathology
- From:
Chinese Journal of Applied Clinical Pediatrics
2015;(20):1528-1531
- CountryChina
- Language:Chinese
-
Abstract:
Maturity-onsetdiabetesoftheyoung(MODY),amonogenicformofdiabetes,hasmorethan8 well-known subtypes:MODY1( hepatocyte nuclear factor - 4A,HNF4A ),MODY2( glucokinase,GCK ),MODY3 (hepatocyte nuclear factor-1A,HNFIA),MODY4(pancreatic and duodenal homeobox,PDX),MODY5(hepatocyte nuclear factor-1B,HNFIB),MODY6(neuronal differentiation 1,NEUR0DI),MODY7(carboxyl ester lipase,CEL) and MODY8( insulin,INS). The molecular pathology,clinical manifestations and treatment of MODYs are different and reviewed.
