Immune response of neutrophil against candida infection
10.3760/cma.j.issn.1674-2397.2015.05.019
- VernacularTitle:嗜中性粒细胞抗假丝酵母菌感染的免疫作用
- Author:
Tianwen HOU
;
Xiaolin YIN
;
Wei LI
- Publication Type:Journal Article
- Keywords:
Neutrophil;
Candida;
Immunity;
Neutrophil extracellular traps
- From:
Chinese Journal of Clinical Infectious Diseases
2015;(5):476-480
- CountryChina
- Language:Chinese
-
Abstract:
Neutrophil ( PMN) is the main immune effect cell of killing candida yeast cells .It can recognize different cellular components of candida through a variety of surface and intracellular pattern recognition receptors , phagocytose and/or form extracellular traps to capture candida yeast and mycelia , then kill them with oxidation or non-oxidation mechanism .It can also adjust innate immunity and adaptive immune response in candida infection by interaction with other immune cells .This article reviews recent progress of the multiple subsets of neutrophil , the mechanism of its recognizing and killing candida , and the interaction with other immune cells , to provide new perspectives for clinical therapy of candida infections .
