Companion diagnosis for personalized targeted therapy in lung cancer
10.3760/cma.j.issn.1009-9158.2015.10.001
- VernacularTitle:肺癌个体化靶向治疗伴随诊断的新进展
- Author:
Xiaohong HAN
;
Yinchen SHEN
;
Yuankai SHI
- Publication Type:Journal Article
- Keywords:
Lung neoplasms;
Individualized medicine;
High-throughput nucleotide sequencing
- From:
Chinese Journal of Laboratory Medicine
2015;(10):649-652
- CountryChina
- Language:Chinese
-
Abstract:
As the precision medicine has been proposed , personalized therapy in cancer steps into a new stage.Since the development of gene molecular biology in lung cancer , numerous molecular targets were discovered.However, selecting patients who will be the most likely to benefit from the therapy is still a great challenge in clinical practice .Companion diagnosis could help evaluate the status of patients , which may provide better suggestions for health care professionals during treatment decision , in order to benefit the patients and decline the side effects risk together .Besides, high-throughput sequencing technics and diverse detection samples has provided a novel direction to understand the tumorigenesis and find more potential gene targets.
