The application for diagnosis and treatment and the progress for detection methods of circulating microRNAs in colorectal cancer
10.3760/cma.j.issn.1009-9158.2015.10.002
- VernacularTitle:外周血 microRNAs 在结直肠癌诊疗中的应用及检测方法进展
- Author:
Weiwei LIU
;
Tingting HU
;
Ming GUAN
- Publication Type:Journal Article
- Keywords:
Colorectal neoplasms;
microRNAs;
Tumor markers,biological
- From:
Chinese Journal of Laboratory Medicine
2015;(10):653-656
- CountryChina
- Language:Chinese
-
Abstract:
microRNAs as novel tumor biomarkers exert important clinical value in early screening and antidiastole of human cancers .They show a broad prospect in clinical application , particularly due to their low invasive and high sensitivity .This review focused on the application of circulating microRNA for diagnosis and monitoring treatment in colorectal cancer based on the recent findings .Meanwhile, the defects in clinical practice by using microRNAs as tumor biomarkers and the major causes which could constraint their application, especially the unreliable detection result caused by many factors , have been discussed.
