The application of mitomycin-C in refractory esophageal strictures
10.16571/j.cnki.1008-8199.2015.11.022
- VernacularTitle:丝裂霉素C在顽固性食管狭窄中的应用进展
- Author:
Yijia CHEN
;
Guozhong JI
- Publication Type:Journal Article
- Keywords:
Mitomycin C;
Esophageal;
Refractory Stricture
- From:
Journal of Medical Postgraduates
2015;(11):1209-1212
- CountryChina
- Language:Chinese
-
Abstract:
Gastrointestinal benign stricture is one of common diseases in clinics , endoscopic dilation is its preferred treatment . However , for the dilation ineffective refractory strictures , it represents a difficult management problem given the limited therapeutic in-terventions available .Mitomycin-C is an antibiotic which has the dual role of anti-tumor and anti-proliferation.As an anti-proliferative drug, it was first applied in the field of ophthalmology .Local auxiliary application of MMC can be a feasible and safe measurement to improve the efficacy of refractory esophageal strictures .The aim of this study is to perform a systematic review which employs mitomycin C in the treatment of refractory esophageal strictures caused by corrosion , endoscopic submucosal dissection , esophageal atresia repara-tion and radiotherapy .
