Voltage-gated potassium channels in cognitive dysfunction
10.16571/j.cnki.1008-8199.2015.11.024
- VernacularTitle:电压门控性钾通道与认知功能障碍的研究进展
- Author:
Wenhui YAN
;
Meng WANG
;
Lina CHEN
- Publication Type:Journal Article
- Keywords:
Cognitive dysfunction;
Voltage-gated potassium channel;
Delayed rectifier potassium channel;
Transient outward potassium channel;
N-methyl-D-aspartic acid receptor
- From:
Journal of Medical Postgraduates
2015;(11):1218-1222
- CountryChina
- Language:Chinese
-
Abstract:
The growing number of cognitive dysfunction patients is bringing heavy mental and financial burdens to the society and families.Voltage-gated potassium channels (Kv), which consist of delayed rectifier potassium channels and transient outward po -tassium channels , are involved in the incidence of cognitive dysfunction .This review summarized the role of Kv channels in cognitive dysfunction and their relationship with N-methyl-D-aspartic acid receptors ( NMDARs) that play an important role in the process of learning and memory .
