Quality Standard ofPing-AnPill

VernacularTitle:平安丸的质量控制研究＊
Author: Lin QIU ; Ying LIU ; Yuanyuan ZHANG ; Wanyi LI
Publication Type:Journal Article
Keywords: Ping-An Pill; costunolide; dehydrocostunolide; TLC; HPLC
From: World Science and Technology-Modernization of Traditional Chinese Medicine 2015;(9):1883-1889
CountryChina
Language:Chinese
Abstract: This study was aimed to revise and improve the quality standard of Ping-An (PA) Pill. Fructus CaryophylliandFructus Aurantii ImmaturuswereidentifiedbyTLC.Thecontentofcostunolideand dehydrocostunolide were determined by HPLC. The results showed that there were clear spots, good degree of separation, and no negative interference in the TLC identification. The calibration curve of costunolide and dehydrocostunolide were linear at the range of 0.103 4-1.033 5μg (r=0.999 9) and 0.110 1-1.100 5μg (r=0.999 7). The average recoveries were 95.1% (RSD = 2.62%, n = 6) and 98.6% (RSD = 2.84%, n = 6), respectively. It was concluded that the method was convenient and accurate with strong specificity in the quality and quantity control of PA pill, which can be used in the quality control of PA pill.