Topical anesthetic effects of compound lidocaine cream coated endotracheal tube to prevent cough and agitation during extubation in thyroidectomy under general anesthesia
- VernacularTitle:复方利多卡因乳膏涂抹气管导管表面预防甲状腺手术全麻拔管期呛咳躁动
- Author:
Nuoer SANG
;
Ge QU
;
Xiuhua ZHANG
;
Ailun LUO
;
Yuguang HUANG
- Publication Type:Journal Article
- Keywords:
compound lidocaine cream;
topical anesthesia;
thyroidectomy;
cough/agitation during extubation
- From:
Basic & Clinical Medicine
2015;(1):86-89
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the topical anesthetic effects of compound lidocaine cream ( CLC) coated endo-tracheal tube on the prevention of cough/agitation during extubation in thyroidectomy under general anesthesia . Methods 42 patients scheduled for thyroidectomy in Peking Union Medical College Hospital were continuously en -rolled in this prospective double-blinded randomized controlled trial .Patients were randomized into two groups . Group L were intubated with endotracheal tube coated with CLC , while the control group , group C with liquid par-affin .The end point of study was spontaneous or induced cough /agitation during extubation .Hemodynamic parame-ters and the consumption of opioids were recorded .Patients were followed for major complications during their stay in hospital .Results Spontaneous cough/agitation rate was lower in group L than group C ( 15% vs 65%, P<0.01 );so was induced cough/agitation (35%vs 90%, P<0.001 );the value of SBP ×HR was lower in group L at 1 min after extubation ( P<0.05 ) .Conclusions The topical anesthetic effects of CLC coated endotracheal tube could prevent cough and agitation during extubation in thyroidectomy under general anesthesia .
