Related factors about microcirulatory injury following elective PCI for elder patients with stable angina
10.3969/j.issn.1006-5725.2015.20.009
- VernacularTitle:稳定性心绞痛老年患者经皮冠脉介入治疗后发生微循环障碍的相关因素分析
- Author:
Zhengdong WANG
;
Ping LI
;
Zhihai LIN
;
Jianting GAN
- Publication Type:Journal Article
- Keywords:
Angina pectoris;
PCI;
Microcirulation
- From:
The Journal of Practical Medicine
2015;(20):3314-3317
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate microvascular injury-related factors post-percutaneous coronary intervention (PCI). Methods Seventy-two elderly patients with stable angina , who underwent PCI from February 2009 to February 2014, were enrolled in this study. The index of microvascular resistance (IMR) was assessed and the clinical data were collected. The correlation between general clinical data and the IMR value before and after PCI were analyzed, and regression analysis was conducted on the relevant factors with postoperative microcirculation after PCI. Results After PCI, FFR, CFR, CK-MB, troponin were higher than those before PCI, with significant differences (P < 0.05). Linear regression analysis result showed that glycated hemoglobin, the degree of stenosis after PCI were positively correlated with IMR, but ejection fraction and CFR before PCI were negatively correlated with IMR. Conclusion Clinically, diabetes, severe vascular stenosis, low ejection fraction, low CFR before PCI in patients with unstable angina may likely occur microcirculation after PCI.