Value of ultrasound guided fine-needle aspiration cytology in the diagnosis of thyroid nodules

VernacularTitle:超声引导下细针抽吸细胞学检查对甲状腺结节的诊断价值
Author: Teng MA ; Qiang ZHU ; Wenyuan SHI ; Chunxia XIA ; Minxia HU
Publication Type:Journal Article
Keywords: Ultrasonography; Thyroid Nodule; Diagnosis; fine needle aspiration
From: Chinese Archives of Otolaryngology-Head and Neck Surgery 2015;(10):507-515
CountryChina
Language:Chinese
Abstract: [ABSTRACT]OBJECTIVETo evaluate the clinical value of ultrasound guided fine-needle aspiration (US-FNA) in the diagnosis of thyroid nodules with different size.METHODSThe clinical data of 122 thyroid nodules of 109 cases referred to FNAC for diagnosis were retrospectively reviewed. The final operating histological results of 122 nodules were considered gold standard. RESULTSNon-diagnostic FNAC results occurred in 17 nodules (13.9%). FNAC achieved a sensitivity of 78.6%, a specificity of 93.9%, a positive predictive value of 93.6%, a negative predictive value of 78.3%, and a total accuracy of 85.7%. There was no significant difference between the diameter of the nodule≤1 cm group and>1 cm group, except negative predictive value. The non-diagnostic results rate was no significant difference between groups of different nodule size, benign or malignant nodules, and different operators. CONCLUSIONFNAC is a sensitive, specific and accurate method for differential diagnosis of thyroid nodules.