Analgesia nociception index guides remifentanil administration during general anesthesia in posterior lumbar spinal surgery
- VernacularTitle:镇痛／伤害性刺激指数指导瑞芬太尼在全麻腰椎后路手术中的应用
- Author:
Duan YI
;
Bin WEI
;
Liping ZHANG
;
Xiangyang GUO
- Publication Type:Journal Article
- Keywords:
analgesia nociception index;
heart rate variability;
bispectral index;
general anesthesia
- From:
Basic & Clinical Medicine
2015;(10):1341-1345
- CountryChina
- Language:Chinese
-
Abstract:
Objective_To evaluate the clinical profile of ANI-guided remifentanil administration during posterior lumbar spinal surgery.Methods_Sixty patients undergoing selective posterior lumbar decompression laminectomy and internal fixation were randomized into two groups, ANI-guided analgesia group ( ANI group) and another group which was blinded to ANI ( control group) .In both groups, combined propofol-remifentanil target control infusion ( TCI) was performed, In ANI group, the concentration of remifentanil was adjusted to maintain ANI values be-tween 50 and 70, however, in the control group, remifentanil target concentration was adapted corresponding to HR or BP values.Anesthetics consumption, incidence of unwanted events, interventions, time of open-eyes and extu-bation, VAS0h and VAS1/2h, complementary analgesics, intraoperative awareness, PONV and other symptoms were recorded.Results_Remifentanil consumption was lower in ANI group than that in control group ( P<0.05) . The number of unwanted events( hypotension, bradycardia and total unwanted events) were also less in ANI group than that in control group (P<0.05).Compared with control group, the usage of urapidil was more and the usage of volume expansion was less in ANI group( P<0.05) .There was no significant statistic differences in other index
between two groups.Conclusions_ANI-guided remifentanil infusion resulted in application of lower remifentanil administered dose with more stable hemodynamics in posterior lumbar spinal surgery.
