A TiO2/CNTs Nanocomposites Enhanced Luminol Electrochemiluminescence Assay for Glucose Detection
10.11895/j.issn.0253-3820.140957
- VernacularTitle:基于TiO2/CNTs纳米复合物增敏作用电致化学发光法检测葡萄糖的研究
- Author:
Yonghong WANG
;
Faliang LI
;
Yuanqing WANG
;
Shun WU
;
Xiaoxiao HE
;
Kemin WANG
- Publication Type:Journal Article
- Keywords:
Titanium dioxide/carbon nanotubes nanocomposites;
Luminol,Electrochemiluminescence;
Glucose
- From:
Chinese Journal of Analytical Chemistry
2015;(11):1682-1687
- CountryChina
- Language:Chinese
-
Abstract:
Abstract A novel luminol electrochemiluminescence strategy based on titanium dioxide/carbon nanotubes ( TiO2/CNTs) nanocomposites for detection of glucose was developed. First, the TiO2/CNTs nanocomposites were prepared by a sol-gel method and modified on the glassy carbon electrode. The electrochemiluminescence ( ECL) signal could be greatly enhanced when the electrode was established by the nanocomposites, which finally resulted in the increased sensitivity. Glucose oxidase calalyzed the oxidation of glucose to form H2 O2 , and the H2 O2 reacted with luminol to produce the ECL signal. Thus the above system was proved to be efficient for glucose detection. The modified electrode exhibited excellent ECL signals and a good linear range of 1. 0í10-7-5. 0í10-6 mol/L with a detection limit of 5. 2í10-8 mol/L towards glucose detection. This strategy was successfully demonstrated as a sensitive, rapid, simple and cost-effective method to detect glucose. Meanwhile, the TiO2/CNTs nanocomposites offered a novel material for the signal enhancement in electrochemiluminescence sensor.
