Transrectal Real-time Elastography Combined with Dynamic Contrast Material-enhanced Magnetic Resonance Imaging for the Diagnosis of Benign and Malignant Prostate Lesions
10.11969/j.issn.1673-548X.2015.10.017
- VernacularTitle:弹性成像联合磁共振动态增强检查对前列腺良恶性病变诊断的临床应用
- Author:
Ying CHANG
;
Jingchun YANG
;
Xianggong DUAN
- Publication Type:Journal Article
- Keywords:
Prostate cancer;
Transrectal ultrasound;
Elastography;
Magnetic resonance imaging;
Biopsy
- From:
Journal of Medical Research
2015;44(10):60-63
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the value of transrectal real -time elastography ( TRTE) with dynamic contrast material -en-hanced magnetic resonance imaging (DCE-MRI) for prostate cancer detection.Methods A total of 60 men (mean age 71years, range 43 to 83) with serum PSA levels of greater than 4.0ng/ml were assessed using gray -scale transrectal ultrasound (TRUS), transrectal real-time elastography ( TRTE ) and dynamic contrast material -enhanced magnetic resonance imaging ( DCE -MRI ) .Subsequently , these patients underwent systematic sextant transrectal biopsy and additional biopsies for positive sites on gray -scale TRUS, TRTE and DCE-MRI.The cancer detection rates of the 3 techniques were compared .Results Cancer was detected in 23 of the 60 patients (23/60,38.3%).TRTE and DCE-MRI had a higher sensitivity, specificity and accuracy of 73.9%,78.3%,87.0%,80.1%,75.1%, 89.2%,78.3%,76.7%,88.3%respectively.TRTE and DCE-MRI guided targeted biopsy improve the positive detection rate of pros-tate cancer, compared with TRUS (P<0.05).Conclusion TRTE and DCE-MRI can improve the detection rate of the increase of ser-um PSA in patients with prostate cancer , so as to improve the positive rate of prostate biopsy diagnosis ,provide strong support for clinical diagnosis
