Progress of the relationship between autophagy and breast cancer chemotherapy resistance
- VernacularTitle:乳腺癌化疗抗性与自噬的关系研究进展
- Author:
Jingyao CHEN
;
Fei LI
;
Xiaoping YU
- Publication Type:Journal Article
- Keywords:
autophagy;
breast cancer;
chemoresistance
- From:
Basic & Clinical Medicine
2015;(10):1393-1396
- CountryChina
- Language:Chinese
-
Abstract:
The therapy to different type of breast cancer has resulted in chemoresistance which is induced by auto-phagy.Autophagy, to tumor’s generation, is a double edged sword, and it can result to chemoresistance and auto-phagic cell death through interaction with apoptosis in breast cancer chemotherapy.However, autophagy may be unrelated to chemoresistance.It will be a key research point to further explore the relationship and mechanism be-tween autophagy and chemoresistance.