Progress on proteomics of exosomes from tumor cell
- VernacularTitle:恶性肿瘤外泌体蛋白质组学研究进展
- Author:
Zhonghua XIAO
;
Jiawei MIAO
- Publication Type:Journal Article
- Keywords:
malignant tumor;
exosomes;
proteomics;
progress
- From:
Basic & Clinical Medicine
2015;(10):1406-1409
- CountryChina
- Language:Chinese
-
Abstract:
Exosomes are vesicles of endocytic origin released from different cell types under both normal and pathological conditions.Proteomics is an emerging discipline for studying composition and mechanics and interac-tion of proteins with regard to disease occurrence、cellular metabolism,etc.Progress of research on exosomes from tumor cell at proteomics technology platforms in aspect of clarifying mechanisms of shaping and sustaining micro-enviroment of tumor growth and survival and metastasis, induce tumor proliferation, Immunosuppressive effects or immune evasion, and discovering biomarker, makes a promising prospect of exsomes in clinical diagnosis and treatment.
