Origin, existence form, and function of circulating microRNAs associated with cardiovascular disease
10.16571/j.cnki.1008-8199.2015.10.019
- VernacularTitle:心血管疾病相关的循环miRNA的来源与存在形式及其功能
- Author:
Xiaomin BU
;
Feng WANG
- Publication Type:Journal Article
- Keywords:
MiRNAs;
Circulation;
Microvesicle;
Cardiovascular disease
- From:
Journal of Medical Postgraduates
2015;28(10):1091-1094
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNAs ( miRNAs) play an important role in regulating various life activities .It has been confirmed that circulat-ing miRNAs are new biomarkers for the diagnosis of many diseases and closely related with their occurrence and progression .In recent years, miRNAs are found to exist stably in blood and other body fluids in forms of being encapsulated in microvesicle or binding with proteins.Their origins, existence forms and functions have become a hotspot of research in this field .This article reviews the recent studies on the origin , existence form and function of circulating miRNAs associated with cardiovascular disease , aiming to provide some evidence for miRNAs as the biomarker and target of cardiovascular disease .
