Role of cell apoptosis in cardiopulmonary bypass related lung injury

VernacularTitle:细胞凋亡在体外循环肺损伤中的研究进展
Author: Miao HE
Publication Type:Journal Article
Keywords: Cell apoptosis; Cardiopulmonary bypass; Lung injury; Hematopoietic regulatory mechanisms
From: Journal of Medical Postgraduates 2015;28(10):1102-1106
CountryChina
Language:Chinese
Abstract: Cardiopulmonary bypass (CPB) related lung injury is the most common complication in cardiac surgery .Ischemia reperfusion injury and systemic inflammatory reaction may be the important causes of CPB -related lung injury , but the specific mecha-nism is still to be elucidated.In recent years, apoptosis is paid increasing attention in the pathogenesis of CPB .Therefore, cell apopto-sis has been a hot spot in the research of CPB related lung injury .This article summarizes the latest researches on the characteristics , reasons and mechanisms of CPB-related pneumonocyte apoptosis .