Effect Evaluation of Spironolactone in the Treatment of Hypertensive Heart Disease by the Real Time 3 -dimensional Echocardiography
10.11969/j.issn.1673-548X.2015.10.046
- VernacularTitle:实时三维超声心动图对螺内酯治疗高血压性心脏病的效果评价分析
- Author:
Yaxi ZHANG
;
Zhimin CHENG
;
Aihua ZHENG
- Publication Type:Journal Article
- Keywords:
Real time 3-dimensional echocardiography;
Spironolactone;
Hypertensive heart disease
- From:
Journal of Medical Research
2015;44(10):161-163
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect evaluation of spironolactone in the treatment of hypertensive heart disease by the real time 3-dimensional echocardiography .Methods Totally 104 patients with hypertensive heart disease were in the study from Jan 2011 to Jan 2012 of our department and divided into objective group and control group .Conventional treatments were put in all the patients and the spironolactone was used in objective group patients only .The results of ventricular morphology and function indexes were compared be -tween the two groups, and then investigate the relationship between cystatin C (CycC) and left ventricular remodeling index (LVRI) at the same time.Results There were significant differences in the comparison of ventricular morphology and function indexes .The left ventric-ular end-diastolic volume(LVEDV), left ventricular end systolic volume (LVESV) and left ventricular ejection fraction (LVEF) of ob-jective group were more advantageous than flowse of control group for prognosis .The same results were observed in the comparison of Cys C and LVRI.Moreover, Cyc C and LVRI had certain correlation in the study .Conclusion The spironolactone can play a positive role in the treatment for the patients with hypertensive heart disease .In the meantime, the RT-3DE is a good evaluation method for the develop-ment of ventricular morphology and function .
