Application of three-dimensional power Doppler in diagnosing and treating gestational trophoblastic disease
10.7652/jdyxb201506021
- VernacularTitle:三维能量彩色多普勒超声在妊娠滋养细胞疾病诊治中的应用
- Author:
Wei WANG
;
Zhen HAN
;
Xueye TIAN
;
Ting ZHANG
;
Yanyan WANG
;
Ruifang AN
- Publication Type:Journal Article
- Keywords:
three-dimensional ultrasound;
power Doppler;
gestational trophoblastic disease;
diagnosis
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
2015;(6):819-823
- CountryChina
- Language:Chinese
-
Abstract:
Objective To clarify the reliability of three-dimensional power Doppler as a quantitative method in detecting gestational trophoblastic disease (GTD ) and assessing its therapeutic effect. Methods We prospectively collected a database of 52 patients with GTD diagnosed at the First Affiliated Hospital of Xi’an Jiaotong University from December 201 1 to October 2013 and 30 healthy women as controls.Sonography was performed using a Voluson E8. Resistance index (RI ), vascularization index (VI ), flow index (FI ) and vascularization-flow index (VFI)of the region of interest were collected for further analysis.Results Of the 52 GTD datasets,variation from the mean value was RI 0.47±0.1 7;VI (81.46 ±20.54)%;FI 67.28 ±20.21;and VFI 58.12±25.53.Three-dimensional power Doppler examination indicated that there were significant differences in RI,VI,FI and VFI values between healthy individuals and patients in each subgroup (P <0.01).Further,after combining invasive hydatidiform mole and choriocarcinoma groups,it also showed a significant difference between hydatidiform mole group and the combined malignant group (P <0.01).And the abnormal sonographic and power Doppler findings in GTD were resolved when chemotherapy was given successfully.Conclusion RI,VI,FI and VFI values were more related to the information of tumor blood flow,and more intuitive to manifest the status of the disease.They could be new methods in diagnosing and assessing treatment of GTD for their real-time nature.
