Observation of the clinical efficacy of Shenfuyishen Capsule in the treatment of diabetic nephropathy in high altitude regions
10.7652/jdyxb201506026
- VernacularTitle:参附益肾胶囊治疗高海拔地区糖尿病肾病的临床观察
- Author:
Wenjuan WANG
;
Xin DENG
- Publication Type:Journal Article
- Keywords:
diabetic nephropathy;
Shenfuyishen Capsule;
high-altitude region;
yangxu xueyu;
wangla
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
2015;(6):845-848
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical efficacy of Shenfuyishen Capsule in the treatment of diabetic nephropathy of yangxuxueyu type in high- altitude regions.Methods We divided 53 patients randomly into two groups:31 in the observation group and 22 in the control group.Patients in the control group were treated with conventional regime of Western Medicine.Those in treatment group were given extra treatment with Shenfuyishen Capsule.Then we tested serum creatinine (Scr ),uric acid (UA),urinary microalbumin (MALB )and GFR. Results The total efficiency was 90.32% and 81.82% in the treatment group and the control group,which was significantly different (P < 0.05 ).Major symptoms improved after treatment in both groups,which differed significantly compared with those before treatment (P <0.05).ALT in the treatment group was not different after treatment.CR,UA,MALB and GFR significantly differed before and after treatment in both groups,especially in the treatment group (P <0.05).Conclusion Shenfuyishen Capsule helps improve major clinical symptoms and decrease CR,GFR,UA and MLAB levels in patients with diabetic nephrology,thus protecting renal function and delaying the process of diabetic nephropathy.