Effect of acute non-isovolemic hemodilution in combination with tranexamic acid on cycle function blood gas and electrolytes with brain tumor surgery
10.3969/j.issn.1006-5725.2015.19.041
- VernacularTitle:急性非等容性血液稀释联合氨甲环酸对脑肿瘤手术患者循环功能和血气电解质的影响
- Author:
Xibao LUO
;
Yumin ZHU
;
Zhigui LIU
;
Zhihua HUANG
;
Xiangling QIN
;
Shuwen ZHAI
- Publication Type:Journal Article
- Keywords:
Acute non-isovolemic hemodilution;
Tranexamic acid;
Brain tumor surgery
- From:
The Journal of Practical Medicine
2015;(19):3244-3246
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of acute non-isovolemic hemodilution in combination with tranexamic acid on cycle function blood gas and electrolytes with brain tumor surgery. Methods Forty-two patients undergoing brain tumor were randomly divided into two groups. Patients in group A received ANIH plus tranexamic acid , while patients in group B received ANIH alone. Collected blood was transfused before the end of surgery. HR、CVP、MAP,hemoglubin, blood gas and plasma electrolytes were respectively recorded before ANIH(T1), at 0 min (T1) and 1 h (T2) after ANIH, and at the end of operation (T4). Results There were no significant changes in HR, CVP, MAP. At T2, T3, T4, Hb, Hct in both two groups lower than those at T1(P <0.05); at T4, Hb, Hct in group A were higher than those in group B. There were no significant changes in pH , PaO2, PaCO2, BE between the both two groups. There were no significant changes in Na +, Cl-, Ca2+and K+between the both two groups. Conclusion ANIH has little effect on the cycle function and blood gas electrolyte. ANIH in combination with TA has a section blood effect. It can be used in the brain tumor operation with TA security.
