The clinical significance of dynamic contrast-enhanced MR of the breast in evaluating residuals after lumpectomy
10.3969/j.issn.1006-5725.2015.18.020
- VernacularTitle:MR动态增强检查在评估乳腺肿块切除术后恶性残留中的临床价值
- Author:
Yun HU
;
Shutong ZHANG
;
Chaolin JIN
;
Xiang WANG
;
Zheng WANG
- Publication Type:Journal Article
- Keywords:
Lumpectomy;
Residual;
MR imaging;
Dynamic contrast-enhanced imaging
- From:
The Journal of Practical Medicine
2015;(18):3000-3003
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the efficacy of dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) of the breast in the detection of residual lesions of early stage breast carcinoma after lumpectomy. Methods 53 patients with breast masses confirmed to be malignant tumors by pathology after lumpectomy underwent the dynamic contrast-enhanced breast MR imaging and then further surgical treatment by lumpectomy. The DCE MRI-based diagnoses were compared to the results of pathological analyses after the second lumpectomy. Results 17 (32%) cases were detected with abnormal enhancement. 8 cases presented mass-like enhancements , and 6 of them showed tumorous residuals (P < 0.01). 6 presented focal enhancements, taking up 35% and one of them was confirmed pathologically to have tumorous residuals (P < 0.01). 3 cases presented mass-like enhancement, taking up 18% and 2 of them were confirmed with cancerous residuals . MR dynamic enhancement showed 68% of the them presented no abnormal enhancements in the breast and 33 of themhad no residual cancer , taking up 92%. 3 of them were confirmed with tumorous residuals , taking up 8%. The The positive predictive value and negative predictive value of DCE MR imaging for diagnosing residual malignant lesion were 52% and 92%, respectively . Conclusion The dynamic contrast-enhanced MRI of breast is helpful for evaluating residual malignant lesion after lumpectomy and affects positively subsequent treatment.
