The application of high viscosity bone cement in treating severe osteoporotic vertebral body compression fractures
10.3969/j.issn.1008-794X.2015.09.018
- VernacularTitle:高黏骨水泥在骨质疏松性严重椎体压缩骨折中的应用
- Author:
Dashou WANG
;
Qian CHEN
;
Chunshan LUO
;
Yu QIN
;
Qi PAN
;
Fengjun CAI
;
Aicun XUE
;
Hong SONG
;
Tingsheng LU
;
Yan CHEN
;
Liang ZHANG
;
Ruihong HUANG
;
Wei WANG
- Publication Type:Journal Article
- Keywords:
vertebroplasty;
osteoporosis;
severe vertebral body compression;
high viscosity bone cement;
visual analogue scale;
life quality score;
complication
- From:
Journal of Interventional Radiology
2015;(9):815-818
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the short-term curative effect and the safety of percutaneous vertebroplasty using high viscosity bone cement for the treatment of severe osteoporotic vertebral body compression fractures. Methods The clinical data of 100 patients with severe osteoporotic vertebral body compression fractures (compression degree>70%), who received percutaneous vertebroplasty by using high viscosity bone cement during the period from December 2010 to May 2013, were retrospectively analyzed. All the patients were followed up for at least one month. Both preoperative and postoperative visual analogue scale (VAS) and quality of life (QOL) scores, as well as the incidence of bone cement leakage, were recorded and the results were used to evaluate the curative effect and the safety of percutaneous vertebroplasty for severe osteoporotic vertebral body compression fractures. Results One week after the treatment, significant pain relief was obtained in 92 patients (92%), VAS scores decreased from preoperative (7.0 ±1.2) to postoperative (2.0±1.5), and QOL scores increased from preoperative (30±5.0) to postoperative (80±18.0);the differences were statistically significant (P<0.01). One month after the treatment, significant pain relief was seen in 91 patients (91%), VAS scores decreased from preoperative (7.0 ±1.2) to postoperative (1.5 ±1.0) and QOL scores increased from preoperative (30±5.0) to postoperative (80±15.0); the differences were statistically significant (P<0.01). No statistically significant differences in VAS scores and QOL scores existed between the data determined at one week after the treatment and the data determined at one month after the treatment (P>0.05). Leakage of bone cement was observed in 40 patients (40%), resulting no severe neurological symptoms; among the 40 patients, intervertebral disc leakage at above and below the vertebral body was detected in 28 patients (70%), vertebral anterior edge leakage was observed in 11 patients (27.5%) and vertebral posterior edge leakage was seen in one patient (2.5%). Conclusion For the treatment of severe osteoporotic vertebral body compression fractures, percutaneous vertebroplasty by using high viscosity bone cement is safe and effective.
