Study on the relationship of metabolizing enzyme CBS G919A gene polymorphism with essential hypertension on Hui nationality in Xinjiang
10.3969/j.issn.1006-5725.2015.19.012
- VernacularTitle:新疆回族原发性高血压与胱硫醚β合成酶G919A多态性的相关性
- Author:
Lei ZHAO
;
Lei ZHANG
;
Dongsheng RUI
- Publication Type:Journal Article
- Keywords:
Essential hypertension;
CBS G919A;
Gene polymorphism;
Hui nationality
- From:
The Journal of Practical Medicine
2015;(19):3156-3158
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the relationship of metabolizing enzyme Cystathionine βsynthase (CBS) G919A gene polymorphism with essential hypertension on Hui nationality in Xinjiang. Methods Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was used to detect the gene polymorphism, blood lipid, blood sugar and other biochemical indicators were tested at the same time. Result The distribution frequency of genotype GG, GA, AA and A,G, of CBS G919A was 76.4%, 19.0%, 4.5%, which was of no significant difference compared with the control group (P > 0.05). Conclusion Gene polymorphism of CBS G919A was existed, which was no relationship with essential hypertension on Hui nationality in Xinjiang.
